Blood Transfusion Verification Initiation and Reaction Response

Key Points

  • Transfusion safety starts with strict compatibility verification and two-clinician check protocol.
  • Blood administration requires dedicated blood tubing with filter and correct priming setup.
  • Early recognition of transfusion reactions is a time-critical nursing responsibility.
  • Suspected reaction requires immediate stop-transfusion response and escalation.

Equipment

  • Provider order, transfusion consent, and blood-bank documentation
  • Blood product with complete label data and compatibility verification materials
  • Dedicated blood tubing with filter and normal saline prime/flush setup per policy
  • Vital-sign monitoring equipment and emergency-response resources
  • Documentation and incident/escalation workflow tools

Procedure Steps

  1. Verify order, indication, consent, and patient identity before obtaining blood product.
  2. At bedside, complete two-clinician verification of patient and product identifiers.
  3. Confirm product type, compatibility (ABO/Rh/crossmatch details), serial number, and expiration.
  4. Use only approved blood tubing/filter and prime per policy.
  5. Obtain baseline assessment and vital signs before starting transfusion.
  6. Start transfusion at ordered initial rate and remain with patient during early monitoring window.
  7. Reassess vitals/symptoms at required intervals and document response throughout infusion.
  8. Complete product documentation (type, volume, times, verification details, patient response).
  9. If reaction suspected, stop transfusion immediately, maintain IV patency with normal saline per policy, notify provider and blood bank, and follow reaction protocol.
  10. Continue close reassessment and complete all required reaction reporting/documentation.

Common Errors

  • Incomplete bedside verification life-threatening incompatibility risk.
  • Wrong tubing setup or missing filter clot/particulate safety risk.
  • Delayed action on early symptoms (fever, dyspnea, rash, hypotension) escalation to severe reaction.
  • Inadequate documentation of verification and reaction details unsafe continuity and legal risk.