Factors Affecting Sexual Health and Function Across the Lifespan

Key Points

  • Sexual function is influenced by physiology, mental health, social context, and medication exposure.
  • Common contributors include chronic disease, pain, mobility limits, stress, body-image concerns, and relationship conflict.
  • Sexual dysfunction can involve desire, arousal, orgasm, or pain and often has multifactorial causes.
  • Lifespan changes alter sexual expression but do not eliminate the need for sexual-health assessment.

Pathophysiology

Sexual function requires integrated vascular, neurologic, endocrine, musculoskeletal, and cognitive-emotional coordination. Disruption in any system can reduce desire, arousal, comfort, or satisfaction.

Chronic illness and treatment burden can reduce energy, alter sensation, and impair confidence in intimacy. Psychological distress and stigma may amplify physiologic symptoms, creating a reinforcing cycle of avoidance and dysfunction.

Classification

  • Physiologic contributors: Aging changes, endocrine variation, chronic disease, pain, mobility impairment.
  • Medication/substance contributors: Drug-induced desire/arousal/orgasm changes and sedation-related effects.
  • Psychological contributors: Stress, anxiety, depression, trauma history, body-image distress.
  • Psychosocial contributors: Relationship strain, cultural/religious norms, discrimination, social isolation.

Nursing Assessment

NCLEX Focus

Assess sexual concerns with a multimodal lens; single-cause assumptions often miss treatable factors.

  • Assess symptom pattern by domain: desire, arousal, orgasm, pain, and relationship impact.
  • Assess chronic conditions and mobility limitations affecting sexual participation.
  • Assess medication list for known sexual side effects and timing relationships.
  • Assess psychosocial context including stress load, support quality, and safety concerns.

Nursing Interventions

  • Integrate sexual-function screening into chronic-disease and medication follow-up visits.
  • Provide tailored education on modifiable factors (for example symptom management, safer-sex strategies, communication).
  • Collaborate with interdisciplinary specialists for persistent or complex dysfunction.
  • Reinforce realistic, nonstigmatizing expectations for sexuality across all life stages.

Underassessment Harm

Failure to assess sexual function can prolong distress, undermine relationships, and reduce quality of life.

Pharmacology

Multiple drug classes can affect desire, arousal, and orgasm; evaluate risks and consider adjustment pathways when clinically appropriate while preserving primary disease control.

Clinical Judgment Application

Clinical Scenario

A patient with diabetes and cardiovascular disease reports new erectile difficulties and relationship strain.

Recognize Cues: Functional sexual change with comorbid disease and psychosocial impact. Analyze Cues: Likely mixed vascular, medication, and stress-related contributors. Prioritize Hypotheses: Priority is comprehensive, nonjudgmental etiologic assessment. Generate Solutions: Review medications, optimize disease control, and provide targeted counseling/referral. Take Action: Coordinate interprofessional plan and follow-up monitoring. Evaluate Outcomes: Improved function, communication, and quality-of-life measures.

Self-Check

  1. Why is sexual dysfunction often multifactorial in chronic disease?
  2. Which medication review steps are essential when sexual function changes?
  3. How do psychosocial stressors alter physiologic sexual response?